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Ebolavirus polymerase uses an unconventional genome replication mechanism

Most nonsegmented negative strand (NNS) RNA virus genomes have complementary 3′ and 5′ terminal nucleotides because the promoters at the 3′ ends of the genomes and antigenomes are almost identical to each other. However, according to published sequences, both ends of ebolavirus genomes show a high d...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Deflubé, Laure R., Cressey, Tessa N., Hume, Adam J., Olejnik, Judith, Haddock, Elaine, Feldmann, Friederike, Ebihara, Hideki, Fearns, Rachel, Mühlberger, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486738/
https://ncbi.nlm.nih.gov/pubmed/30962389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815745116
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