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Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53
A population-restricted single-nucleotide coding region polymorphism (SNP) at codon 47 exists in the human TP53 gene (P47S, hereafter P47 and S47). In studies aimed at identifying functional differences between these variants, we found that the African-specific S47 variant associates with an impaire...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486733/ https://ncbi.nlm.nih.gov/pubmed/30962386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821277116 |
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