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Hypothalamic‐pituitary‐adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia

BACKGROUND: Glucocorticoids play a major role in the treatment of acute lymphoblastic leukaemia (ALL). However, supraphysiological doses can suppress the hypothalamic‐pituitary‐adrenal (HPA) axis. HPA axis suppression resulting in reduced cortisol response may cause an impaired stress response and a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cochrane Database Syst Rev
Prif Awduron: Rensen, Niki, Gemke, Reinoud JBJ, van Dalen, Elvira C, Rotteveel, Joost, Kaspers, Gertjan JL
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley & Sons, Ltd 2017
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486149/
https://ncbi.nlm.nih.gov/pubmed/29106702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD008727.pub4
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