Hypothalamic‐pituitary‐adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia

BACKGROUND: Glucocorticoids play a major role in the treatment of acute lymphoblastic leukaemia (ALL). However, supraphysiological doses can suppress the hypothalamic‐pituitary‐adrenal (HPA) axis. HPA axis suppression resulting in reduced cortisol response may cause an impaired stress response and a...

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Vydáno v:Cochrane Database Syst Rev
Hlavní autoři: Rensen, Niki, Gemke, Reinoud JBJ, van Dalen, Elvira C, Rotteveel, Joost, Kaspers, Gertjan JL
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486149/
https://ncbi.nlm.nih.gov/pubmed/29106702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD008727.pub4
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