Phase 1 trial of recombinant Modified Vaccinia Ankara (MVA) encoding Epstein-Barr viral tumor antigens in nasopharyngeal carcinoma patients

Epstein-Barr virus (EBV) is associated with several malignancies including nasopharyngeal carcinoma (NPC), a high incidence tumor in Chinese populations, in which tumor cells express the two EBV antigens EBNA1 and LMP2. Here we report the Phase I trial of a recombinant vaccinia virus, MVA-EL, which...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Hui, Edwin P, Taylor, Graham S, Jia, Hui, Ma, Brigette BY, Chan, Stephen L, Ho, Rosalie, Wong, WL, Wilson, Steven, Johnson, Benjamin F, Edwards, Ceri, Stocken, Deborah D, Rickinson, Alan B, Steven, Neil M, Chan, Anthony TC
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485495/
https://ncbi.nlm.nih.gov/pubmed/23348421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2448
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