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Phase 1 trial of recombinant Modified Vaccinia Ankara (MVA) encoding Epstein-Barr viral tumor antigens in nasopharyngeal carcinoma patients

Epstein-Barr virus (EBV) is associated with several malignancies including nasopharyngeal carcinoma (NPC), a high incidence tumor in Chinese populations, in which tumor cells express the two EBV antigens EBNA1 and LMP2. Here we report the Phase I trial of a recombinant vaccinia virus, MVA-EL, which...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Hui, Edwin P, Taylor, Graham S, Jia, Hui, Ma, Brigette BY, Chan, Stephen L, Ho, Rosalie, Wong, WL, Wilson, Steven, Johnson, Benjamin F, Edwards, Ceri, Stocken, Deborah D, Rickinson, Alan B, Steven, Neil M, Chan, Anthony TC
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485495/
https://ncbi.nlm.nih.gov/pubmed/23348421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2448
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