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Preactivated thiomers: evaluation of gastroretentive minitablets

The object of this study was to evaluate the potential of a recently developed preactivated thiolated pectin derivative as mucoadhesive excipient in drug delivery to the gastric cavity. Pectin (Pec) was chemically modified with L-cysteine (Cys). The free thiol groups of resulting thiomer were activa...

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Publicado en:Int J Pharm
Autores principales: Hauptstein, Sabine, Müller, Christiane, Dünnhaupt, Sarah, Laffleur, Flavia, Bernkop-Schnürch, Andreas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485488/
https://ncbi.nlm.nih.gov/pubmed/23999225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2013.08.032
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