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Thiomer-coated liposomes harbor permeation enhancing and efflux pump inhibitory properties

An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimid...

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Detalhes bibliográficos
Main Authors: Gradauer, K., Dünnhaupt, S., Vonach, C., Szöllösi, H., Pali-Schöll, I., Mangge, H., Jensen-Jarolim, E., Bernkop-Schnürch, A., Prassl, R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560037/
https://ncbi.nlm.nih.gov/pubmed/23228848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.12.001
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