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Synthesis and in vitro characterization of entirely S-protected thiolated pectin for drug delivery

The study was aimed to synthesize a thiolated polymer (thiomer) that is resistant to oxidation in solutions above pH 5. In order to protect a pectin-cysteine conjugate against premature oxidation, the thiomer was S-protected by a disulfide connected leaving group. Therefore, 2-mercaptonicotinic acid...

詳細記述

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書誌詳細
出版年:Eur J Pharm Biopharm
主要な著者: Hintzen, Fabian, Hauptstein, Sabine, Perera, Glen, Bernkop-Schnürch, Andreas
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485494/
https://ncbi.nlm.nih.gov/pubmed/24095893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2013.09.017
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