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SumHer better estimates the SNP heritability of complex traits from summary statistics

We present SumHer, software for estimating confounding bias, SNP heritability, enrichments of heritability and genetic correlations using summary statistics from genome-wide association studies. The key difference between SumHer and the existing software LD Score Regression (LDSC) is that SumHer all...

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Bibliografische gegevens
Gepubliceerd in:Nat Genet
Hoofdauteurs: Speed, Doug, Balding, David J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485398/
https://ncbi.nlm.nih.gov/pubmed/30510236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0279-5
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