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SumHer better estimates the SNP heritability of complex traits from summary statistics

We present SumHer, software for estimating confounding bias, SNP heritability, enrichments of heritability and genetic correlations using summary statistics from genome-wide association studies. The key difference between SumHer and the existing software LD Score Regression (LDSC) is that SumHer all...

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Détails bibliographiques
Publié dans:Nat Genet
Auteurs principaux: Speed, Doug, Balding, David J
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485398/
https://ncbi.nlm.nih.gov/pubmed/30510236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0279-5
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