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SumHer better estimates the SNP heritability of complex traits from summary statistics

We present SumHer, software for estimating confounding bias, SNP heritability, enrichments of heritability and genetic correlations using summary statistics from genome-wide association studies. The key difference between SumHer and the existing software LD Score Regression (LDSC) is that SumHer all...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Speed, Doug, Balding, David J
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485398/
https://ncbi.nlm.nih.gov/pubmed/30510236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0279-5
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