HOXB13 networking with ABCG1/EZH2/Slug mediates metastasis and confers resistance to cisplatin in lung adenocarcinoma patients

Rationale: Distant metastasis and chemoresistance are the major causes of short survival after initial chemotherapy in lung adenocarcinoma patients. However, the underlying mechanisms remain elusive. Our pilot study identified high expression of the homeodomain transcription factor HOXB13 in chemore...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Zhan, Jun, Wang, Peng, Li, Shuai, Song, Jiagui, He, Huiying, Wang, Yunling, Liu, Zhaofei, Wang, Fan, Bai, Hua, Fang, Weigang, Du, Quan, Ye, Min, Chang, Zhijie, Wang, Jie, Zhang, Hongquan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485289/
https://ncbi.nlm.nih.gov/pubmed/31037158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29463
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