miR-26a Limits Muscle Wasting and Cardiac Fibrosis through Exosome-Mediated microRNA Transfer in Chronic Kidney Disease

Uremic cardiomyopathy and muscle atrophy are associated with insulin resistance and contribute to chronic kidney disease (CKD)-induced morbidity and mortality. We hypothesized that restoration of miR-26a levels would enhance exosome-mediated microRNA transfer to improve muscle wasting and cardiomyop...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Wang, Bin, Zhang, Aiqing, Wang, Haidong, Klein, Janet D., Tan, Lin, Wang, Ze-Mu, Du, Jie, Naqvi, Nawazish, Liu, Bi-Cheng, Wang, Xiaonan H.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485283/
https://ncbi.nlm.nih.gov/pubmed/31037144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29579
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