Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy

miR-155 was synthesized and loaded into exosomes in increased infiltration of macrophages in a uremic heart. The released exosomal fusion with the plasma membrane leads to the release of miR-155 into the cytosol and translational repression of forkhead transcription factors of the O class (FoxO3a) i...

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Bibliografske podrobnosti
izdano v:JACC Basic Transl Sci
Main Authors: Wang, Bin, Wang, Ze-Mu, Ji, Jia-Ling, Gan, Weihua, Zhang, Aiqing, Shi, Hao-Jie, Wang, Hao, Lv, Linli, Li, Zuolin, Tang, Taotao, Du, Jie, Wang, Xiaonan H., Liu, Bi-Cheng
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
PRECLINICAL RESEARCH
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046511/
https://ncbi.nlm.nih.gov/pubmed/32140622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.10.011
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