Exogenous miR-29a Attenuates Muscle Atrophy and Kidney Fibrosis in Unilateral Ureteral Obstruction Mice

Renal fibrosis leads to end-stage renal disease, but antifibrotic drugs are difficult to develop. Chronic kidney disease often results in muscle wasting, and thereby increases morbidity and mortality. In this work, adeno-associated virus (AAV)-mediated overexpressing miR-29a was hypothesized to coun...

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Vydáno v:Hum Gene Ther
Hlavní autoři: Wang, Bin, Wang, Juan, He, Wei, Zhao, Yajie, Zhang, Aiqing, Liu, Yan, Hassounah, Faten, Ma, Fuying, Klein, Janet D., Wang, Xiaonan H., Wang, Haidong
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087404/
https://ncbi.nlm.nih.gov/pubmed/31950871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2019.287
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