Activity and molecular targets of pioglitazone via blockade of proliferation, invasiveness and bioenergetics in human NSCLC

BACKGROUND: Pioglitazone, a synthetic peroxisome proliferator activated receptor (PPAR-γ) ligand, is known as an antidiabetic drug included in the thiazolidinediones (TZDs) class. It regulates the lipid and glucose cell metabolism and recently a role in the inhibition of numerous cancer cell process...

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Bibliografische gegevens
Gepubliceerd in:J Exp Clin Cancer Res
Hoofdauteurs: Ciaramella, Vincenza, Sasso, Ferdinando Carlo, Di Liello, Raimondo, Corte, Carminia Maria Della, Barra, Giusi, Viscardi, Giuseppe, Esposito, Giovanna, Sparano, Francesca, Troiani, Teresa, Martinelli, Erika, Orditura, Michele, De Vita, Ferdinando, Ciardiello, Fortunato, Morgillo, Floriana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485164/
https://ncbi.nlm.nih.gov/pubmed/31027492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1176-1
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