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Ral Signals through a MAP4 Kinase-p38 MAP Kinase Cascade in C. elegans Cell Fate Patterning
C. elegans vulval precursor cell (VPC) fates are patterned by an epidermal growth factor (EGF) gradient. High-dose EGF induces 1o VPC fate, and lower dose EGF contributes to 2o fate in support of LIN-12/Notch. We previously showed that the EGF 2o-promoting signal is mediated by LET-60/ Ras switching...
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| Udgivet i: | Cell Rep |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484852/ https://ncbi.nlm.nih.gov/pubmed/30184501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.011 |
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