Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma

Abnormal increases in nucleolar size and number caused by dysregulation of ribosome biogenesis has emerged as a hallmark in the majority of spontaneous cancers. The observed ribosome hyperactivity can be directly induced by the MYC transcription factors controlling the expression of RNA and protein...

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Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Hald, Øyvind H., Olsen, Lotte, Gallo-Oller, Gabriel, Elfman, Lotta Helena Maria, Løkke, Cecilie, Kogner, Per, Sveinbjörnsson, Baldur, Flægstad, Trond, Johnsen, John Inge, Einvik, Christer
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484764/
https://ncbi.nlm.nih.gov/pubmed/30542116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0611-7
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