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Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma
Abnormal increases in nucleolar size and number caused by dysregulation of ribosome biogenesis has emerged as a hallmark in the majority of spontaneous cancers. The observed ribosome hyperactivity can be directly induced by the MYC transcription factors controlling the expression of RNA and protein...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484764/ https://ncbi.nlm.nih.gov/pubmed/30542116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0611-7 |
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