Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1

Methods to measure cellular target engagement are increasingly being used in early drug discovery. The Cellular Thermal Shift Assay (CETSA) is one such method. CETSA can investigate target engagement by measuring changes in protein thermal stability upon compound binding within the intracellular env...

全面介紹

Na minha lista:
書目詳細資料
發表在:SLAS Discov
Main Authors: Shaw, Joseph, Dale, Ian, Hemsley, Paul, Leach, Lindsey, Dekki, Nancy, Orme, Jonathan P., Talbot, Verity, Narvaez, Ana J., Bista, Michal, Martinez Molina, Daniel, Dabrowski, Michael, Main, Martin J., Gianni, Davide
格式: Artigo
語言:Inglês
出版: SAGE Publications 2018
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484527/
https://ncbi.nlm.nih.gov/pubmed/30543471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218813332
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍