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Development of high throughput screening methods for inhibitors of ClpC1P1P2 from Mycobacteria tuberculosis

Tuberculosis affects about 100 million people worldwide and causes nearly 2 million deaths annually. It has been estimated that one third of all humans is infected with latent Mycobacterium tuberculosis (Mtb). Moreover, Mtb has become increasingly resistant to available antibiotics. Consequently, it...

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Publicado en:Anal Biochem
Main Authors: Fraga, Hugo, Rodriguez, Beatriz, Bardera, Ana, Cid, Concha, Akopian, Tatos, Kandror, Olga, Park, Annie, Colmenarejo, Gonzalo, Lelievre, Joel, Goldberg, Alfred
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484444/
https://ncbi.nlm.nih.gov/pubmed/30543804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2018.12.004
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