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Mutant Lef1 controls Gata6 in sebaceous gland development and cancer

Mutations in Lef1 occur in human and mouse sebaceous gland (SG) tumors, but their contribution to carcinogenesis remains unclear. Since Gata6 controls lineage identity in SG, we investigated the link between these two transcription factors. Here, we show that Gata6 is a β‐catenin‐independent transcr...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Oulès, Bénédicte, Rognoni, Emanuel, Hoste, Esther, Goss, Georgina, Fiehler, Ryan, Natsuga, Ken, Quist, Sven, Mentink, Remco, Donati, Giacomo, Watt, Fiona M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484415/
https://ncbi.nlm.nih.gov/pubmed/30886049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100526
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