Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis

Although acne is the most common human inflammatory skin disease, its pathogenic mechanisms remain incompletely understood. Here we show that GATA6, which is expressed in the upper pilosebaceous unit of normal human skin, is down-regulated in acne. GATA6 controls keratinocyte proliferation and diffe...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Oulès, Bénédicte, Philippeos, Christina, Segal, Joe, Tihy, Matthieu, Vietri Rudan, Matteo, Cujba, Ana-Maria, Grange, Philippe A., Quist, Sven, Natsuga, Ken, Deschamps, Lydia, Dupin, Nicolas, Donati, Giacomo, Watt, Fiona M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575575/
https://ncbi.nlm.nih.gov/pubmed/33082341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18784-z
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