Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties

The epidermis is maintained by multiple stem cell populations whose progeny differentiate along diverse, and spatially distinct, lineages. Here we show that the transcription factor Gata6 controls the identity of the previously uncharacterized sebaceous duct (SD) lineage and identify the Gata6 down-...

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Udgivet i:Nat Cell Biol
Main Authors: Donati, Giacomo, Rognoni, Emanuel, Hiratsuka, Toru, Liakath-Ali, Kifayathullah, Hoste, Esther, Kar, Gozde, Kayikci, Melis, Russel, Roslin, Kretzschmar, Kai, Mulder, Klaas, Teichmann, Sarah, Watt, Fiona M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610974/
https://ncbi.nlm.nih.gov/pubmed/28504705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3532
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