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Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly

Intraflagellar transport (IFT) relies on motor proteins and the IFT complex to construct cilia and flagella. The IFT complex subunit IFT22/RabL5 has sequence similarity with small GTPases although the nucleotide specificity is unclear because of non‐conserved G4/G5 motifs. We show that IFT22 specifi...

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Bibliographic Details
Published in:EMBO J
Main Authors: Wachter, Stefanie, Jung, Jamin, Shafiq, Shahaan, Basquin, Jerome, Fort, Cécile, Bastin, Philippe, Lorentzen, Esben
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484408/
https://ncbi.nlm.nih.gov/pubmed/30940671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101251
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