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Isotopic tagging of oxidized and reduced cysteines (iTORC) for detecting and quantifying sulfenic acids, disulfides, and free thiols in cells

Oxidative modifications of cysteine residues are an important component in signaling pathways, enzymatic regulation, and redox homeostasis. Current direct and indirect methods detect specific modifications and a general binary population of “free” or “oxidized” cysteines, respectively. In an effort...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Albertolle, Matthew E., Glass, Sarah M., Trefts, Elijah, Guengerich, F. Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484142/
https://ncbi.nlm.nih.gov/pubmed/30850396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.007225
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