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Isotopic tagging of oxidized and reduced cysteines (iTORC) for detecting and quantifying sulfenic acids, disulfides, and free thiols in cells

Oxidative modifications of cysteine residues are an important component in signaling pathways, enzymatic regulation, and redox homeostasis. Current direct and indirect methods detect specific modifications and a general binary population of “free” or “oxidized” cysteines, respectively. In an effort...

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Pubblicato in:J Biol Chem
Autori principali: Albertolle, Matthew E., Glass, Sarah M., Trefts, Elijah, Guengerich, F. Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484142/
https://ncbi.nlm.nih.gov/pubmed/30850396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.007225
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