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Isotopic tagging of oxidized and reduced cysteines (iTORC) for detecting and quantifying sulfenic acids, disulfides, and free thiols in cells

Oxidative modifications of cysteine residues are an important component in signaling pathways, enzymatic regulation, and redox homeostasis. Current direct and indirect methods detect specific modifications and a general binary population of “free” or “oxidized” cysteines, respectively. In an effort...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Albertolle, Matthew E., Glass, Sarah M., Trefts, Elijah, Guengerich, F. Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484142/
https://ncbi.nlm.nih.gov/pubmed/30850396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.007225
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