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Isotopic tagging of oxidized and reduced cysteines (iTORC) for detecting and quantifying sulfenic acids, disulfides, and free thiols in cells

Oxidative modifications of cysteine residues are an important component in signaling pathways, enzymatic regulation, and redox homeostasis. Current direct and indirect methods detect specific modifications and a general binary population of “free” or “oxidized” cysteines, respectively. In an effort...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Albertolle, Matthew E., Glass, Sarah M., Trefts, Elijah, Guengerich, F. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484142/
https://ncbi.nlm.nih.gov/pubmed/30850396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.007225
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