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Defining the mechanism of action of S1QELs, specific suppressors of superoxide production in the quinone-reaction site in mitochondrial complex I

Site-specific suppressors of superoxide production (named S1QELs) in the quinone-reaction site in mitochondrial respiratory complex I during reverse electron transfer have been previously reported; however, their mechanism of action remains elusive. Using bovine heart submitochondrial particles, we...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Banba, Atsushi, Tsuji, Atsuhito, Kimura, Hironori, Murai, Masatoshi, Miyoshi, Hideto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484130/
https://ncbi.nlm.nih.gov/pubmed/30824536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007687
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