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Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I by chemical biology approaches
NADH–quinone oxidoreductase (respiratory complex I) couples NADH-to-quinone electron transfer to the translocation of protons across the membrane. Even though the architecture of the quinone-access channel in the enzyme has been modeled by X-ray crystallography and cryo-EM, conflicting findings rais...
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| Gepubliceerd in: | J Biol Chem |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6333890/ https://ncbi.nlm.nih.gov/pubmed/30425100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006056 |
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