Enhanced osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis: a study based on a three-dimensional biomimetic environment

The mechanism of pathological osteogenesis in Ankylosing spondylitis (AS) is largely unknown. Our previous studies demonstrated that the imbalance between BMP-2 and Noggin secretion induces abnormal osteogenic differentiation of marrow-derived mesenchymal stem cells (MSCs) from AS patients in a two-...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Zheng, Guan, Xie, Zhongyu, Wang, Peng, Li, Jinteng, Li, Ming, Cen, Shuizhong, Tang, Su’an, Liu, Wenjie, Ye, Guiwen, Li, Yuxi, Wang, Shan, Wu, Xiaohua, Su, Hongjun, Wu, Yanfeng, Shen, Huiyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484086/
https://ncbi.nlm.nih.gov/pubmed/31024000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1586-1
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