TRAF4 positively regulates the osteogenic differentiation of mesenchymal stem cells by acting as an E3 ubiquitin ligase to degrade Smurf2

TNF receptor-associated factor 4 (TRAF4), a member of the TRAF family, plays an important role in the embryogenesis and development of the bone system. Mesenchymal stem cells (MSCs), which are the primary origin of osteoblasts in vivo, are key cells in bone development; however, whether TRAF4 modula...

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Bibliographic Details
Published in:	Cell Death Differ
Main Authors:	Li, Jinteng, Wang, Peng, Xie, Zhongyu, Wang, Shan, Cen, Shuizhong, Li, Ming, Liu, Wenjie, Tang, Su’an, Ye, Guiwen, Zheng, Guan, Su, Hongjun, Ma, Mengjun, Wu, Xiaohua, Wu, Yanfeng, Shen, Huiyong
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group UK 2019
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7224386/ https://ncbi.nlm.nih.gov/pubmed/31076633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0328-3
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TRAF4 positively regulates the osteogenic differentiation of mesenchymal stem cells by acting as an E3 ubiquitin ligase to degrade Smurf2

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