Interleukin-6/interleukin-6 receptor complex promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells

BACKGROUND: Interleukin-6 (IL-6) with IL-6 receptor (IL-6R) play an important role in the tissue regeneration in vivo, especially bone metabolism. Bone marrow -derived mesenchymal stem cells (BM-MSCs) are multipotent stromal cells, which are main origin of osteoblasts. However, the roles of IL-6 and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Stem Cell Res Ther
Main Authors: Xie, Zhongyu, Tang, Su’an, Ye, Guiwen, Wang, Peng, Li, Jinteng, Liu, Wenjie, Li, Ming, Wang, Shan, Wu, Xiaohua, Cen, Shuizhong, Zheng, Guan, Ma, Mengjun, Wu, Yanfeng, Shen, Huiyong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776773/
https://ncbi.nlm.nih.gov/pubmed/29357923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0766-0
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