IL-1 receptor antagonist therapy mitigates placental dysfunction and perinatal injury following Zika virus infection

Zika virus (ZIKV) infection during pregnancy causes significant adverse sequelae in the developing fetus, and results in long-term structural and neurologic defects. Most preventive and therapeutic efforts have focused on the development of vaccines, antivirals, and antibodies. The placental immunol...

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Publicado en:JCI Insight
Main Authors: Lei, Jun, Vermillion, Meghan S., Jia, Bei, Xie, Han, Xie, Li, McLane, Michael W., Sheffield, Jeanne S., Pekosz, Andrew, Brown, Amanda, Klein, Sabra L., Burd, Irina
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483652/
https://ncbi.nlm.nih.gov/pubmed/30944243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122678
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