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IL-1 receptor antagonist therapy mitigates placental dysfunction and perinatal injury following Zika virus infection

Zika virus (ZIKV) infection during pregnancy causes significant adverse sequelae in the developing fetus, and results in long-term structural and neurologic defects. Most preventive and therapeutic efforts have focused on the development of vaccines, antivirals, and antibodies. The placental immunol...

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Pubblicato in:JCI Insight
Autori principali: Lei, Jun, Vermillion, Meghan S., Jia, Bei, Xie, Han, Xie, Li, McLane, Michael W., Sheffield, Jeanne S., Pekosz, Andrew, Brown, Amanda, Klein, Sabra L., Burd, Irina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483652/
https://ncbi.nlm.nih.gov/pubmed/30944243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122678
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