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Quod erat demonstrandum? The mystery of experimental validation of apparently erroneous computational analyses of protein sequences

BACKGROUND: Computational predictions are critical for directing the experimental study of protein functions. Therefore it is paradoxical when an apparently erroneous computational prediction seems to be supported by experiment. RESULTS: We analyzed six cases where application of novel or convention...

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Hlavní autoři: Iyer, Lakshminarayan M, Aravind, L, Bork, Peer, Hofmann, Kay, Mushegian, Arcady R, Zhulin, Igor B, Koonin, Eugene V
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC64836/
https://ncbi.nlm.nih.gov/pubmed/11790254
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