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Quod erat demonstrandum? The mystery of experimental validation of apparently erroneous computational analyses of protein sequences

BACKGROUND: Computational predictions are critical for directing the experimental study of protein functions. Therefore it is paradoxical when an apparently erroneous computational prediction seems to be supported by experiment. RESULTS: We analyzed six cases where application of novel or convention...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Principais autores: Iyer, Lakshminarayan M, Aravind, L, Bork, Peer, Hofmann, Kay, Mushegian, Arcady R, Zhulin, Igor B, Koonin, Eugene V
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64836/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11790254/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/gb-2001-2-12-research0051
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