Quod erat demonstrandum? The mystery of experimental validation of apparently erroneous computational analyses of protein sequences

BACKGROUND: Computational predictions are critical for directing the experimental study of protein functions. Therefore it is paradoxical when an apparently erroneous computational prediction seems to be supported by experiment. RESULTS: We analyzed six cases where application of novel or convention...

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Bibliographic Details
Main Authors: Iyer, Lakshminarayan M, Aravind, L, Bork, Peer, Hofmann, Kay, Mushegian, Arcady R, Zhulin, Igor B, Koonin, Eugene V
Format: Artigo
Language:Inglês
Published: BioMed Central 2001
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC64836/
https://ncbi.nlm.nih.gov/pubmed/11790254
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