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Mechanisms of in utero cortisol effects on the newborn heart revealed by transcriptomic modeling
We have identified effects of elevated maternal cortisol (induced by maternal infusion 1 mg·kg(−1)·day(−1)) on fetal cardiac maturation and function using an ovine model. Whereas short-term exposure (115–130-day gestation) increased myocyte proliferation and Purkinje fiber apoptosis, infusions until...
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| Publicado no: | Am J Physiol Regul Integr Comp Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483213/ https://ncbi.nlm.nih.gov/pubmed/30624972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00322.2018 |
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