Mechanisms of in utero cortisol effects on the newborn heart revealed by transcriptomic modeling

We have identified effects of elevated maternal cortisol (induced by maternal infusion 1 mg·kg(−1)·day(−1)) on fetal cardiac maturation and function using an ovine model. Whereas short-term exposure (115–130-day gestation) increased myocyte proliferation and Purkinje fiber apoptosis, infusions until...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Antolic, Andrew, Li, Mengchen, Richards, Elaine M., Curtis, Celia W., Wood, Charles E., Keller-Wood, Maureen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483213/
https://ncbi.nlm.nih.gov/pubmed/30624972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00322.2018
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky