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Mechanisms for the adverse effects of late gestational increases in maternal cortisol on the heart revealed by transcriptomic analyses of the fetal septum

We have previously shown in sheep that 10 days of modest chronic increase in maternal cortisol resulting from maternal infusion of cortisol (1 mg/kg/day) caused fetal heart enlargement and Purkinje cell apoptosis. In subsequent studies we extended the cortisol infusion to term, finding a dramatic in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Richards, Elaine M., Wood, Charles E., Rabaglino, Maria Belen, Antolic, Andrew, Keller-Wood, Maureen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121623/
https://ncbi.nlm.nih.gov/pubmed/24867915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00009.2014
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