Blockade of ERK1/2 by U0126 alleviates uric acid-induced EMT and tubular cell injury in rats with hyperuricemic nephropathy

Extracellular signal-regulated kinases 1 and 2 (ERK1/2) are serine/threonine kinases and function as regulators of cellular proliferation and differentiation. Recently, we demonstrated that inhibition of ERK1/2 alleviates the development and progression of hyperuricemia nephropathy (HN). However, it...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Tao, Min, Shi, Yingfeng, Tang, Lunxian, Wang, Yi, Fang, Lu, Jiang, Wei, Lin, Tao, Qiu, Andong, Zhuang, Shougang, Liu, Na
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483027/
https://ncbi.nlm.nih.gov/pubmed/30648910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00480.2018
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