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Blockade of enhancer of zeste homolog 2 alleviates renal injury associated with hyperuricemia

Hyperuricemia has been identified as an independent risk factor for chronic kidney disease (CKD) and is associated with the progression of kidney diseases. It remains unknown whether enhancer of zeste homolog 2 (EZH2), a histone H3 lysine 27 methyltransferase, can regulate metabolism of serum uric a...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Shi, Yingfeng, Xu, Liuqing, Tao, Min, Fang, Lu, Lu, Jiasun, Gu, Hongwei, Ma, Shuchen, Lin, Tao, Wang, Yi, Bao, Wenfang, Qiu, Andong, Zhuang, Shougang, Liu, Na
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734054/
https://ncbi.nlm.nih.gov/pubmed/30566000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00234.2018
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