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Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice

Hepatic steatosis is the beginning phase of nonalcoholic fatty liver disease, and hyperhomocysteinemia (HHcy) is a significant risk factor. Soluble epoxide hydrolase (sEH) hydrolyzes epoxyeicosatrienoic acids (EETs) and other epoxy fatty acids, attenuating their cardiovascular protective effects. Ho...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Am J Physiol Gastrointest Liver Physiol
Κύριοι συγγραφείς: Yao, Liu, Cao, Boyang, Cheng, Qian, Cai, Wenbin, Ye, Chenji, Liang, Jing, Liu, Wenli, Tan, Lu, Yan, Meng, Li, Bochuan, He, Jinlong, Hwang, Sung Hee, Zhang, Xu, Wang, Chunjiong, Ai, Ding, Hammock, Bruce D., Zhu, Yi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Physiological Society 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483021/
https://ncbi.nlm.nih.gov/pubmed/30789748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00148.2018
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