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Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure

Excessive sympathoexcitation characterizes the chronic heart failure (CHF) state. An exaggerated cardiac sympathetic afferent reflex (CSAR) contributes to this sympathoexcitation. Prior studies have demonstrated that the CSAR to capsaicin [transient receptor potential (TRP) vanilloid 1 agonist] is e...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Adam, Ryan J., Xia, Zhiqiu, Pravoverov, Kristina, Hong, Juan, Case, Adam J., Schultz, Harold D., Lisco, Steven J., Zucker, Irving H., Wang, Han-Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483016/
https://ncbi.nlm.nih.gov/pubmed/30707612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00696.2018
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