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MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers

miR-155 has recently emerged as an important promoter of antitumor immunity through its functions in T lymphocytes. However, the impact of T cell–expressed miR-155 on immune cell dynamics in solid tumors remains unclear. In the present study, we used single-cell RNA sequencing to define the CD45(+)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Ekiz, H. Atakan, Huffaker, Thomas B., Grossmann, Allie H., Stephens, W. Zac, Williams, Matthew A., Round, June L., O’Connell, Ryan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482995/
https://ncbi.nlm.nih.gov/pubmed/30721153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126543
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