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Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload
The integration of in vitro cardiac tissue models, human induced pluripotent stem cells (hiPSCs) and genome-editing tools allows for the enhanced interrogation of physiological phenotypes and the recapitulation of disease pathologies. Here, in a cardiac tissue model consisting of filamentous 3D matr...
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| Pubblicato in: | Nat Biomed Eng |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482859/ https://ncbi.nlm.nih.gov/pubmed/31015724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-018-0280-4 |
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