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Self-organizing human cardiac microchambers mediated by geometric confinement

Tissue morphogenesis and organ formation are the consequences of biochemical and biophysical cues that lead to cellular spatial patterning in development. To model such events in vitro, we use PEG-patterned substrates to geometrically confine human pluripotent stem cell colonies and spatially presen...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ma, Zhen, Wang, Jason, Loskill, Peter, Huebsch, Nathaniel, Koo, Sangmo, Svedlund, Felicia L., Marks, Natalie C., Hua, Ethan W., Grigoropoulos, Costas P., Conklin, Bruce R., Healy, Kevin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503387/
https://ncbi.nlm.nih.gov/pubmed/26172574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8413
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