Cargando...

Deletion of leptin receptors in vagal afferent neurons disrupts estrogen signaling, body weight, food intake and hormonal controls of feeding in female mice

Deletion of the leptin receptor from vagal afferent neurons (VAN) using a conditional deletion (Nav1.8/LepR(fl/fl)) results in an obese phenotype with increased food intake and lack of exogenous cholecystokinin (CCK)-induced satiation in male mice. Female mice are partially protected from weight gai...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Am J Physiol Endocrinol Metab
Main Authors: Huang, Kuei-Pin, Ronveaux, Charlotte C., de Lartigue, Guillaume, Geary, Nori, Asarian, Lori, Raybould, Helen E.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482667/
https://ncbi.nlm.nih.gov/pubmed/30753113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00296.2018
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!