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Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity
The vagal afferent pathway senses hormones released from the gut in response to nutritional cues and relays these signals to the brain. We tested the hypothesis that leptin resistance in vagal afferent neurons (VAN) is responsible for the onset of hyperphagia by developing a novel conditional knocko...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142400/ https://ncbi.nlm.nih.gov/pubmed/25161883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.06.003 |
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